Ospemifene
Uses, side effects, interactions and warnings
Ospemifene is a daily prescription tablet for moderate to severe pain during sex caused by vaginal changes after menopause. It acts like oestrogen on the vaginal lining without being a hormone itself. It is an option for women who cannot or prefer not to use vaginal creams.
What is ospemifene used for?
- Painful intercourse (dyspareunia) due to menopause
- Vaginal dryness after menopause
How does ospemifene work?
Ospemifene is a selective oestrogen receptor modulator (SERM). It switches on oestrogen receptors in the vaginal tissue, making the lining thicker and more elastic, while having different effects in other parts of the body.
How is ospemifene taken?
It is taken as one 60 mg tablet once a day with food. Your doctor will review the benefit after a few months and decide how long to continue.
What are the side effects of ospemifene?
- Hot flushes
- Vaginal discharge
- Muscle cramps
- Increased sweating
- Signs of a blood clot or stroke
- Unusual vaginal bleeding
- Severe allergic reaction
Which medicines interact with ospemifene?
Who should be careful with ospemifene?
Not suitable if you have had blood clots, stroke, breast cancer or unexplained vaginal bleeding, or if you could be pregnant. Tell your doctor about liver disease. Availability in India is limited, so your gynaecologist may suggest alternatives.
Frequently asked questions
Is ospemifene a hormone?
No. It is not oestrogen, but it acts like oestrogen on the vaginal lining.
How does it compare with vaginal estradiol?
Both treat menopausal dryness and pain. Vaginal estradiol is used locally; ospemifene is a tablet, which some women find easier.
Does ospemifene cause hot flushes?
It can. Hot flushes are one of its more common side effects.
This information does not replace advice from your doctor or pharmacist. SexologistIndia.com does not sell medicines.