Skip to content
SiSexologistIndia.com
Sign in
SSRIPrescription only · Schedule H

Dapoxetine

Uses, side effects, interactions and warnings

Reviewed by Dr. Arjun Mehta, MD (Psychiatry) · Updated
Generic nameDapoxetine
Drug classSSRI
FormOral tablet
PrescriptionRequired
Starts working1–3 hours
Lasts up toA few hours
Quick answer

Dapoxetine is a short-acting prescription medicine for premature ejaculation in men aged 18 to 64. Taken 1 to 3 hours before sex, it helps delay ejaculation. It can cause dizziness or fainting, so it should not be combined with alcohol or other antidepressants.

What is dapoxetine used for?

  • Premature ejaculation in adult men

How does dapoxetine work?

Dapoxetine is a selective serotonin reuptake inhibitor (SSRI). It briefly increases serotonin activity in the nerves that control ejaculation, which helps delay it. Unlike other SSRIs, it is absorbed and cleared quickly, so it is taken only when needed.

How is dapoxetine taken?

Tablets come in 30 mg and 60 mg strengths. It is taken with a full glass of water 1 to 3 hours before sex, no more than once in 24 hours. Your doctor will usually start with the lower strength and review how you respond.

What are the side effects of dapoxetine?

Common
  • Nausea
  • Dizziness
  • Headache
  • Diarrhoea
  • Trouble sleeping
Get medical help right away
  • Fainting or feeling faint, especially on standing
  • Seizures
  • Mood changes or thoughts of self-harm
  • Severe allergic reaction

Which medicines interact with dapoxetine?

Other SSRIs, SNRIs, MAO inhibitors, lithiumAvoidRisk of serotonin syndrome.
ThioridazineAvoidRisk of serious heart rhythm problems.
Ketoconazole, ritonavir and similar drugsAvoidGreatly raise dapoxetine levels.
PDE5 inhibitors (sildenafil, tadalafil)CautionCan increase dizziness on standing. Use only if your doctor advises.
AlcoholCautionIncreases the risk of fainting and injury.

Who should be careful with dapoxetine?

Do not take dapoxetine if you have heart failure, heart rhythm problems, moderate or severe liver disease, or a history of mania or severe depression. Sit or lie down if you feel lightheaded, and avoid driving if you feel dizzy.

Frequently asked questions

Can I take dapoxetine every day?

No. Dapoxetine is designed to be taken only when needed, no more than once every 24 hours.

Does dapoxetine help with erections?

No. It only delays ejaculation. If you also have erection problems, your doctor may treat them separately.

Are there non-medicine options for premature ejaculation?

Yes. Behavioural techniques such as stop–start and squeeze, pelvic floor exercises and counselling help many men, alone or with medicine.

This information does not replace advice from your doctor or pharmacist. SexologistIndia.com does not sell medicines.