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Azole antifungalAvailable without prescription (vaginal)

Clotrimazole

Uses, side effects, interactions and warnings

Reviewed by Dr. Kavya Iyer, MS (OBG) · Updated
Generic nameClotrimazole
Drug classAzole antifungal
FormVaginal tablet, cream or pessary
PrescriptionNot required
Starts working1–3 days for symptom relief
Quick answer

Clotrimazole is an antifungal medicine used inside the vagina or on the skin to treat yeast infections (thrush). Symptoms such as itching and thick white discharge usually ease within a few days. See a doctor if this is your first infection, it keeps coming back, or you are pregnant.

What is clotrimazole used for?

  • Vaginal yeast infection (candidiasis)
  • Fungal skin infections such as ringworm and jock itch
  • Yeast infection of the penis (balanitis)

How does clotrimazole work?

Clotrimazole damages the cell wall of the Candida yeast, which stops it growing and lets the normal balance of the vagina return.

How is clotrimazole used?

It is commonly used as a single 500 mg vaginal tablet at bedtime, or a cream for several days. Follow the pack or your doctor’s instructions and finish the full course even if symptoms improve.

What are the side effects of clotrimazole?

Common
  • Mild burning or itching
  • Redness
  • Discomfort on application
Get medical help right away
  • Severe allergic reaction
  • Blistering or severe irritation
  • Fever, abdominal pain or foul-smelling discharge (may mean another infection)

Which medicines interact with clotrimazole?

Latex condoms and diaphragmsCautionOil-based creams can weaken latex for a few days.
Tacrolimus (vaginal use)CautionLevels may rise; your doctor may monitor them.

Who should be careful with clotrimazole?

See a doctor before using it if you are pregnant, under 16 or over 60, have more than two infections in 6 months, have abnormal bleeding, or have symptoms of an STI. Partners usually do not need treatment unless they have symptoms.

Frequently asked questions

Can I have sex while using clotrimazole?

It is best to avoid sex until symptoms clear. The cream can also weaken latex condoms.

Can I use clotrimazole during my period?

Vaginal tablets work best when you are not bleeding heavily, but you can use it if needed. Avoid tampons during treatment.

How do I know it is a yeast infection?

Yeast causes itching and thick white discharge. Fishy-smelling discharge suggests bacterial vaginosis, which needs a different medicine.

This information does not replace advice from your doctor or pharmacist. SexologistIndia.com does not sell medicines.